abstract：:The ontogeny of two gonadotropin-releasing-hormone (GnRH) systems, salmon GnRH (sGnRH) and chicken GnRH-II (cGnRH-II), was investigated in zebrafish (Danio rerio). In situ hybridization (ISH) first detected sGnRH mRNA-expressing cells at 1 day post-fertilization (pf) anterior to the developing olfactory organs. Subseq...

journal_title：Cell and tissue research

authors： Palevitch O,Kight K,Abraham E,Wray S,Zohar Y,Gothilf Y

更新日期：2007-02-01 00:00:00

abstract：:Periodontal regeneration requires the coordinated movement and differentiation of several cell types in order to re-establish the cementum, periodontal ligament (PDL), and alveolar bone. Cells in culture are often used as model systems for mature tissues, although they may represent expanded progenitor cell population...

journal_title：Cell and tissue research

authors： Lallier TE,Spencer A

更新日期：2007-01-01 00:00:00

abstract：:Unfertilized eggs commonly lack centrioles, which are usually provided by the male gamete at fertilization, and are unable to assemble functional reproducing centrosomes. However, some insect species lay eggs that develop to adulthood without a contribution from sperm. We report that the oocyte of the parthenogenetic ...

journal_title：Cell and tissue research

authors： Riparbelli MG,Giordano R,Callaini G

更新日期：2006-12-01 00:00:00

abstract：:The alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are the principal molecular units for fast excitatory synaptic transmission in the central nervous system. The glutamate-mediated transmission efficiency of synaptic AMPA receptors is influenced by their subunit composition (GluR-A to GluR-D...

journal_title：Cell and tissue research

authors： Sprengel R

更新日期：2006-11-01 00:00:00

abstract：:Kainate receptors form a family of ionotropic glutamate receptors that appear to play a special role in the regulation of the activity of synaptic networks. This review first describes briefly the molecular and pharmacological properties of native and recombinant kainate receptors. It then attempts to outline the gene...

journal_title：Cell and tissue research

authors： Pinheiro P,Mulle C

更新日期：2006-11-01 00:00:00

abstract：:The dorsal root ganglion (DRG) and dorsal horn of the spinal cord are areas through which primary afferent information passes enroute to the brain. Previous studies have reported that, during normal neuronal activity, the regional distribution of a second messenger, diacylglycerol (DG), which is derived from phosphoin...

journal_title：Cell and tissue research

authors： Sasaki H,Hozumi Y,Hasegawa H,Ito T,Takagi M,Ogino T,Watanabe M,Goto K

更新日期：2006-10-01 00:00:00

abstract：:Caprine preantral follicles within ovarian fragments were cryopreserved in the absence or presence of 0.5 M sucrose with or without 1 M dimethyl sulfoxide and/or 1 M ethylene glycol (EG). After being thawed, they were washed in minimum essential medium with or without 0.3 M sucrose. Histological analysis of follicle i...

journal_title：Cell and tissue research

authors： Santos RR,Tharasanit T,Figueiredo JR,van Haeften T,van den Hurk R

更新日期：2006-09-01 00:00:00

abstract：:5-Hydroxytryptamine (5-HT) is an endogenous stimulant of intestinal propulsive reflexes. It exerts its effects partly through 5-HT4 receptors; 5-HT4 receptor agonists that are stimulants of intestinal transit are in clinical use. Both pharmacological and recent immunohistochemical studies indicate that 5-HT4 receptors...

journal_title：Cell and tissue research

authors： Poole DP,Xu B,Koh SL,Hunne B,Coupar IM,Irving HR,Shinjo K,Furness JB

更新日期：2006-09-01 00:00:00

abstract：:A body of evidence points to the existence of stem cell stores in adult tissues, in addition to the well-known hematopoietic stem cells from bone marrow. Many reports describe the ability of these multipotent cells (developmentally non-compromised with their organs of origin) to give rise to many different cell types ...

journal_title：Cell and tissue research

authors： Freitas CS,Dalmau SR

更新日期：2006-09-01 00:00:00

abstract：:Early in postnatal life, the first wave of spermatogenesis is accompanied by an initial wave of germ cell apoptosis. This may reflect an adjustment in the number of germ cells that can be adequately maintained by Sertoli cells. Two major pathways (intrinsic and extrinsic) are involved in the process of caspase activat...

journal_title：Cell and tissue research

authors： Moreno RD,Lizama C,Urzúa N,Vergara SP,Reyes JG

更新日期：2006-09-01 00:00:00

abstract：:Removal of the somatic DNA methylation pattern from donor cells and remodeling of embryonic status have been suggested as integral processes for successful nuclear transfer (NT) reprogramming. This study has investigated the effects of 5-azacytidine (5-azaC), a DNA methylation inhibitor, on global methylation changes ...

journal_title：Cell and tissue research

authors： Mohana Kumar B,Jin HF,Kim JG,Song HJ,Hong Y,Balasubramanian S,Choe SY,Rho GJ

更新日期：2006-09-01 00:00:00

abstract：:Adrenal medullary chromaffin cells are derivatives of the neural crest and are widely believed to share a common sympathoadrenal (SA) progenitor with sympathetic neurons. For decades, the adrenal cortical environment was assumed to be essential for channelling SA progenitors towards an endocrine chromaffin cell fate. ...

journal_title：Cell and tissue research

authors： Lohr J,Gut P,Karch N,Unsicker K,Huber K

更新日期：2006-09-01 00:00:00

abstract：:In humans, pathogenesis in cyclosporine A (CsA)-induced gingival overgrowth (GO) includes the accumulation of extracellular matrix (ECM) constituents, viz., collagen type-1 and type-3 and proteoglycans, in subgingival connective tissue. However, whether this increase is associated with alterations of molecules pivotal...

journal_title：Cell and tissue research

authors： Dannewitz B,Edrich C,Tomakidi P,Kohl A,Gabbert O,Eickholz P,Steinberg T

更新日期：2006-09-01 00:00:00

abstract：:Our findings suggest that nitric oxide (NO) acts as peripheral neuromodulator in locusts, in which it is commonly co-localized with RF-like peptide in neurosecretory cells. We also present the first evidence for NO as a cardio-regulator in insects. Putative NO-producing neurones were detected in locust pre-genital fre...

journal_title：Cell and tissue research

authors： Bullerjahn A,Mentel T,Pflüger HJ,Stevenson PA

更新日期：2006-08-01 00:00:00

abstract：:Beta-catenin is a multi-functional molecule that is involved in both cell-cell adhesion and signaling. We analyzed changes in beta-catenin gene expression during mouse molar tooth development by in situ hybridization. Prominent up-regulation of the expression of this gene was evident exclusively in the enamel knot at ...

journal_title：Cell and tissue research

authors： Obara N,Suzuki Y,Takeda M

更新日期：2006-07-01 00:00:00

abstract：:Neuronal differentiation is characterized by stereotypical sequences of membrane channel and receptor acquisition. This is regulated by the coordinated interactions of a variety of developmental mechanisms, one of which is the control by steroid hormones. We have used the metamorphosis of the holometabolous insect, Ma...

journal_title：Cell and tissue research

authors： Börner J,Puschmann T,Duch C

更新日期：2006-07-01 00:00:00

abstract：:This study explores the molecular composition of the tight junction (TJ) in human term placenta from normal women and from patients with preeclampsia, a hypertensive disorder of pregnancy. Maternal endothelial dysfunction is a critical characteristic of preeclampsia; hence, we have analyzed its impact on placental ves...

journal_title：Cell and tissue research

authors： Liévano S,Alarcón L,Chávez-Munguía B,González-Mariscal L

更新日期：2006-06-01 00:00:00

abstract：:Experimental autoimmune orchitis (EAO) in the rat is the primary chronic animal model for the investigation of one of the main causes of male infertility, viz., testicular inflammation. Dendritic cells (DC) are potent antigen-presenting cells that play a fundamental role in autoimmune disease. We investigated the numb...

journal_title：Cell and tissue research

authors： Rival C,Lustig L,Iosub R,Guazzone VA,Schneider E,Meinhardt A,Fijak M

更新日期：2006-05-01 00:00:00

abstract：:Using specimens of human submandibular glands, we have investigated in vitro the morphological modifications induced by clozapine, a dibenzodiazepine derivative that is used in psychotic patients and that provokes hypersalivation, a side-effect of therapy. The effects of the drug, used alone or in combination with car...

journal_title：Cell and tissue research

authors： Testa Riva F,Puxeddu R,Loy F,Conti G,Riva A

更新日期：2006-05-01 00:00:00

abstract：:The distribution of somatostatin and cocaine and amphetamine-regulated transcript (CART) was investigated in rat intracardiac ganglia. Somatostatin immunoreactivity was only present in nerve terminals, always colocalised with choline acetyltransferase immunoreactivity, surrounding approximately 10% of intracardiac neu...

journal_title：Cell and tissue research

authors： Richardson RJ,Grkovic I,Anderson CR

更新日期：2006-04-01 00:00:00

abstract：:The periodontal ligament (PDL) is a highly specialized tissue connecting the cementum with the tooth socket bone and affects the life span of the tooth. However, little is known about the precise characteristics and regenerative mechanism of PDL cells because of the absence of specific markers and cell lines. Therefor...

journal_title：Cell and tissue research

authors： Fujii S,Maeda H,Wada N,Kano Y,Akamine A

更新日期：2006-04-01 00:00:00

abstract：:Antithrombin (AT), which is mainly synthesized in the liver, is an acute-phase plasma protein in mammalian species. Here, we demonstrated that sheep anti-human AT antibody cross-reacted with the humoral fluids in amphioxus Branchiostoma belcheri tsingtauense as well as human serum. The concentration of AT in the humor...

journal_title：Cell and tissue research

authors： Liang Y,Zhang S,Lun L,Han L

更新日期：2006-03-01 00:00:00

abstract：:Rat quiescin/sulphydryl oxidase (rQSOX) introduces disulphide bridges into peptides and proteins with the reduction of molecular oxygen to hydrogen peroxide. Its occurrence has been previously highlighted in a wide range of organs by reverse transcription-polymerase chain reaction (RT-PCR) and Northern blot analyses, ...

journal_title：Cell and tissue research

authors： Tury A,Mairet-Coello G,Esnard-Fève A,Benayoun B,Risold PY,Griffond B,Fellmann D

更新日期：2006-01-01 00:00:00

abstract：:Tight junctions (TJ) between retinal pigmented epithelial (RPE) and retinal endothelial cells maintain the outer and inner blood-retinal barrier, and the breakdown of these barriers is associated with retinal diseases. Vascular endothelial growth factor (VEGF) increases vascular permeability and is thought to be invol...

journal_title：Cell and tissue research

authors： Ghassemifar R,Lai CM,Rakoczy PE

更新日期：2006-01-01 00:00:00

abstract：:Nucleoside di-phosphate kinase enzyme (NDPK) isoforms, encoded by the nm23 family of genes, may be involved in various cellular differentiation and proliferation processes. We have therefore analyzed the expression of nm23-M1, -M2, -M3, and -M4 during embryonic mouse development. In situ hybridization data has reveale...

journal_title：Cell and tissue research

authors： Amrein L,Barraud P,Daniel JY,Pérel Y,Landry M

更新日期：2005-12-01 00:00:00

abstract：:Apoptotic and inflammatory processes occur in human arteriosclerotic lesions. We examined the hypothesis whether both processes are possibly associated by studying the colocalization of corresponding markers. In 11 human arteriosclerotic carotid arteries, proapoptotic markers (CPP32 (caspase-3), poly(ADP-ribose) polym...

journal_title：Cell and tissue research

authors： Schlittenhardt D,Schmiedt W,Bonaterra GA,Metz J,Kinscherf R

更新日期：2005-12-01 00:00:00

abstract：:The transient receptor potential (TRP) superfamily comprises a group of non-selective cation channels that have been implicated in both receptor and store-operated channel functions. The family of the classical TRPs (TRPCs) consists of seven members (TRPC1-7). The presence of TRPC1 and TRPC5 mRNA in the brain has prev...

journal_title：Cell and tissue research

authors： von Bohlen Und Halbach O,Hinz U,Unsicker K,Egorov AV

更新日期：2005-11-01 00:00:00

abstract：:Alcohol and aldehyde dehydrogenases (ADHs and ALDHs) may be of interest in the pathology of Parkinson's disease (PD) because of their role in protection against toxins and in retinoid metabolism, which is required for growth and development of the mesencephalic dopamine system. In the present study, the spatial and te...

journal_title：Cell and tissue research

authors： Westerlund M,Galter D,Carmine A,Olson L

更新日期：2005-11-01 00:00:00

abstract：:This review summarizes findings concerning the unique developmental characteristics of mouse head muscles (mainly the masticatory and tongue muscles) and compares their characteristics with those of other muscles. The developmental origin of the masticatory muscles is the somitomeres, whereas the tongue and other musc...

journal_title：Cell and tissue research

authors： Yamane A

更新日期：2005-11-01 00:00:00

abstract：:Adenosine 5'-triphosphate is known to function as a potent extracellular messenger, producing its effects via a distinct family of cell surface receptors. Different receptor subtypes have been shown to modulate different cellular functions such as proliferation, differentiation and apoptosis. We have investigated the ...

journal_title：Cell and tissue research

authors： White N,Butler PE,Burnstock G

更新日期：2005-09-01 00:00:00

abstract：:In the stalk-eyed fly Cyrtodiopsis whitei (Diopsidae; Diptera), the relatively long optic nerve develops within the tight lumen of a very short eyestalk. Axonal growth is generally considered in terms of path finding, selective fasciculation, and towing. Physical forces that are necessary for axon lengthening are gene...

journal_title：Cell and tissue research

authors： Buschbeck EK,Hoy RR

更新日期：2005-09-01 00:00:00

abstract：:The distribution and chemical neuroanatomy of nervous elements and certain pharmacological-physiological characteristics of the innervation of the body wall in earthworms are described. Solitary sensory bipolar cells can be found among the epithelial cells. These bipolar cells contain serotonin, tyrosine hydroxylase, ...

journal_title：Cell and tissue research

authors： Csoknya M,Takács B,Koza A,Dénes V,Wilhelm M,Hiripi L,Kaslin J,Elekes K

更新日期：2005-09-01 00:00:00

abstract：:A technique for organotypic in vitro culture with serum-free medium was tested for its appropriateness to mimic normal odontogenesis in the cichlid fish Hemichromis bimaculatus and the zebrafish Danio rerio. Serial semithin sections were observed by light microscopy to collect data on tooth patterning and transmission...

journal_title：Cell and tissue research

authors： Van der Heyden C,Allizard F,Sire JY,Huysseune A

更新日期：2005-09-01 00:00:00

abstract：:We describe the neurons regulating two separate functions of the pharyngeal retractor muscle (PRM), namely sustained contraction during body withdrawal and rhythmic phasic contractions during feeding, in the snail, Helix pomatia. The distribution of central neurons innervating the PRM is organized into two main units;...

journal_title：Cell and tissue research

authors： Hernádi L,Vehovszky A,Hiripi L,Györi J,Walker RJ,Elekes K

更新日期：2005-08-01 00:00:00

abstract：:The apposition compound eyes of gonodactyloid stomatopods are divided into a ventral and a dorsal hemisphere by six equatorial rows of enlarged ommatidia, the mid-band (MB). Whereas the hemispheres are specialized for spatial vision, the MB consists of four dorsal rows of ommatidia specialized for colour vision and tw...

journal_title：Cell and tissue research

authors： Kleinlogel S,Marshall NJ

更新日期：2005-08-01 00:00:00

abstract：:Mouse milk fat globule-EGF factor 8, MFG-E8, is the ortholog to the human mammary tumor marker, lactadherin, and comprises two spliced variants, the L and S forms. Recent studies have suggested that MFG-E8-L produced by macrophages and Langerhans cells in the skin serves as a linker between phagocytic cells and apopto...

journal_title：Cell and tissue research

authors： Watanabe T,Totsuka R,Miyatani S,Kurata S,Sato S,Katoh I,Kobayashi S,Ikawa Y

更新日期：2005-08-01 00:00:00

abstract：:Pulmonary neuroepithelial bodies (NEBs) are extensively innervated organoid groups of neuroendocrine cells that lie in the epithelium of intrapulmonary airways. Our present understanding of the morphology of NEBs is comprehensive, but direct physiological studies have so far been challenging because the extremely diff...

journal_title：Cell and tissue research

authors： Pintelon I,De Proost I,Brouns I,Van Herck H,Van Genechten J,Van Meir F,Timmermans JP,Adriaensen D

更新日期：2005-07-01 00:00:00

abstract：:The antral hormone gastrin is the key regulator of gastric acid secretion, mucosal growth and differentiation. Gastrin is synthesized in the endocrine G-cells in the antroduodenal mucosa. We have now examined the way in which the loss of gastrin alone or gastrin plus cholecystokinin (CCK) affects the antral G-cell. Im...

journal_title：Cell and tissue research

authors： Friis-Hansen L,Wierup N,Rehfeld JF,Sundler F

更新日期：2005-07-01 00:00:00

abstract：:Transcription factor p53 regulates the cell cycle and apoptosis and may impair angiogenesis by the deregulation of pro-angiogenic factors and the activation of anti-angiogenic factors. Our aim has been to elucidate further the role of p53 in physiological angiogenesis. By treating hamsters with the wildtype p53 inhibi...

journal_title：Cell and tissue research

authors： Bordel R,Laschke MW,Menger MD,Vollmar B

更新日期：2005-06-01 00:00:00

abstract：:The reduced-folate carrier (Rfc-1), previously also called methotrexate carrier-1 (MTX-1), was recently identified as accounting for approximately 30% of the methotrexate (Mtx) uptake into rat kidney slices. The localization of the carrier and its contribution to secretory or reabsorptive flux of the drug was therefor...

journal_title：Cell and tissue research

authors： Kneuer C,Honscha KU,Honscha W

更新日期：2005-06-01 00:00:00